ChemMatrix® - The 100% PEG Matrix
Matrix Innovation has developed a new patented 100% PEG
resin that offers a tremendous advantage over polystyrene
resin for long and difficult peptides. With its highly crosslinked
matrix it has unsurpassed mechanical and thermal stabilities.
Let us present to you ChemMatrix® the 100% PEG matrix.
External surface of a ChemMatrix bead by Focused Ion Beam (FIB).
Section of a ChemMatrix bead by Focused Ion Beam (FIB).
- Higher chemical stability
ChemMatrix® is made exclusively from primary ether bonds which are known to be highly chemically stable. This matrix
is therefore much more stable than any other commercial amphiphilic resins.
- Higher loadings
The standard loadings of commercial amphiphilic resins are mainly from 0,2 up to 0,4 mmol/g. With even a better amphiphilicity
ChemMatrix® has loadings between 0.8 to 1.0 mmol/g, which is up to 3 times the loadings of other PEG resins.
- Purer crude products
ChemMatrix resin has been compared to polystyrene resin for the synthesis of many difficult peptides and the results cleary
demonstrate a huge advantage in using it. Results are shown in the following pages.
- Free flowing
ChemMatrix® is a user friendly resin because it is delivered as free flowing powder. It is easily weighted and transfered with
minimum losses on glassware.
- Higher compatibility with solvents
ChemMatrix® allows the use of almost any kind of solvent, even water. The standard solvents used for polystyrene,
such as dichloromethane and THF, are also very compatible with ChemMatrix®. Some amphiphilic resins are known to have
a good swelling, but the loading and/or the mechanical stability are affected. Usually, these resins become tacky and hard to
handle once solvated. You will be surprised to see how ChemMatrix® is easily filtered and washed with almost any solvents.
 
| 
